System Suitability in an Optimized HPLC System |
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Abstract: | Abstract The relationship between calibration, validation and system suitability is demonstrated within the chemometric framework. The importance of system suitability is stressed and its interrelationship with mobile phase optimization is discussed. In addition, it is shown that sensitivity data generated in a mobile phase optimization study can be used to effectively set system suitability criteria and make improvements to an unacceptable chromatographic system. |
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