用于褪黑素检测的电化学生物传感器研究进展

褪黑素是人体松果体分泌的一种重要的神经递质,近年来其在控制昼夜节律和提供免疫抗炎特性等生理调节作用方面备受关注。因此,发展可靠、快速检测体内和体外样本中褪黑素浓度的方法,对于探索褪黑素的临床应用和生物学特性具有重要的意义。本文对褪黑素及其传统检测方法进行简要介绍,重点阐述了近几年报道的用于生物样本和药物样本中褪黑素定量检测的电化学传感器,并对褪黑素传感器的未来发展方向进行展望。

Advances of electrochemical biosensors for melatonin detection

Melatonin is an important neurotransmitter secreted by the human pineal gland. In recent years it has received much attention for its physiological regulatory role in controlling circadian rhythms and providing immune anti-inflammatory properties. Therefore, the development of reliable and rapid methods for the detection of melatonin concentration in vivo and in vitro is of great significance for exploring the clinical application and biological characteristics of melatonin. In this paper, we give a brief overview of melatonin and traditional methods for melatonin detection. We also highlight the electrochemical sensors reported in recent years for the quantitative detection of melatonin in biological and pharmaceutical samples and provide an outlook on the future direction of melatonin sensors.