气相-红外光谱联用技术鉴定对羟基联苯加氢产物的异构体

对羟基联苯的选择性催化加氢反应是一个平行连串复杂反应,由于反应物的两个苯环加氢的难易程度不同,使得产物中含有两个不同的苯环分别加氢或者全部加氢而生成多个异构体,用通常的分析方法难于对异构体进行区分鉴定。使用气相-红外光谱联用分析手段,通过对苯环的对位和单取代位置的波数特征进行分析,可以鉴定出加氢反应的主产物是对环己基苯酚,副产物是由对环己基环己醇和对苯基环己醇的异构体组成。气-质联用、熔点测定、核磁共振等辅助分析,进一步验证了气相-红外光谱联用分析结果的准确性,表明气-红联用技术是一个快速准确分析具有特征官能团的有机化合物异构体的现代仪器方法。

GC-FTIR Analysis of Structural Isomers from Hydrogenation Products of P-Phenylphenol

The hydrogenation of p-phenylphenol is a consecutive and parallel complex reaction.Owing to the difference in the hydrogenation ability of the two benzene rings in p-phenylphenol,the hydrogenation products contained several structural isomers,which can not be identified by normal analytical method.However,the reaction mixture was effectively separated and identified by GC-FTIR technique.According to the characteristic wave numbers of benzene ring substituted at different positions,the main product was confirmed to be p-cyclohexylphenol,and the two typical by-products were p-phenylcyclohexanol and p-cyclohexylcyclohexanol,respectively.Each product has several stereo-isomers.GC-MS,melting point measurement and NMR proved the accuracy of GC-FTIR results,indicating that GC-IR is an useful and rapid method for analyzing structural isomers of organic compounds.