Reaction of 3‐substituted and 4‐bromo‐3‐substituted isoquinolin‐1‐(2h)‐ones with propargyl bromide |
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Authors: | Cyril Odianose Usifoh |
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Abstract: | Isoquinolinones were brominated using N‐bromosuccinimide in dimethylformamide at room temperature to give 4‐bromo‐3‐substituted isoquinolin‐1‐(2H)‐ones. The reaction of these isoquinolinones with propargyl bromide in the presence of anhydrous potassium carbonate yielded N and O‐alkylated products. |
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