Syntheses,Crystal Structures and Cytotoxities of Silver (I) Complexes of 2,2′‐Bipyridines and 1,10‐Phenanthroline |
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Authors: | Hai‐Liang Zhu Qi Chen Wen‐Lie Peng Sui‐Jian Qi An‐Long Xu Xiao‐Ming Chen |
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Abstract: | The syntheses, characterizations and in vitro cytotoxities of seven soluble silver (I) compounds (1–7) with 2,2′‐bipyridine (bpy), 5,5′‐dimethyl‐2,2′‐bipyridine (dmbpy) and 1, 10‐phenanthroline (phen) are described. Two of the complexes, [Ag(dmbpy)(NO3)] (1) and [Ag(dmbpy)]ClO4(2), have been structurally established by single‐crystal X‐ray diffraction, which reveals the silver(I) atom in compound 1 is in a Y‐shape coordination geometry with two N atoms (av. Ag? N = 227.8 pm) from a chelate dmbpy ligand and an O atom (Ag? O=221.8(4) pm) from a monodentate nitrate. The Ag(I) atom in compound 2 is three‐coordinated by three N atoms, two of which are from a chelate dmbpy, and one from an acetonitrile ligand. The seven compounds showed strong cytotoxities in vitro to both normal and carcinoma cells. |
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Keywords: | 2,2′ ‐Bipyridine 1,10‐phenanthroline silver(I) crystal structure cytotoxity |
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