New ganoderic acids, bioactive triterpenoid metabolites from the mushroom Ganoderma lucidum |
| |
| Authors: | Li Canjun Li Yiming Sun Hao H |
| |
| Affiliation: | Pharmanex Shanghai R&D, Building 11, Bi Po Rd, Shanghai 201203, China. |
| |
| Abstract: | Two new lanostanoids, 7-oxo-ganoderic acid Z (1) and 15-hydroxy-ganoderic acid S (2), were isolated from a lipophilic extract of the fruiting body of Ganoderma lucidum. The structures of both compounds were established by interpretation of their spectroscopic data. Compounds 1 and 2 both exhibited inhibitory activities against the HMG-CoA reductase and acyl CoA acyltransferase. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
