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Polycarboxylated Derivatives of b.beta;-Cyclodextrin |
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| Authors: | Francesco Trotta Paolo Ferruti Elisabetta Ranucci Massimo Veglia Claudio Baggiani Cristina Giovannoli |
| Affiliation: | (1) Dipartimento di Chimica Organica Industriale dell'Universitá, Via Venezian 21, 21100 Milano, Italy.;(2) Dipartimento di Chimica Organica Industriale dell'Universitá, Via Venezian 21, 21100 Milano, Italy;(3) Dipartimento di Chimica dell'Universitá, Via Branze 18 Brescia, Torino, Italy;(4) Dipartimento di Chimica Analitica dell'Universitá, Via Giuria 5, 10125 Torino, Italy |
| Abstract: | The synthesis of polycarboxylated derivatives of  -cyclodextrin obtained by reacting maleic anhydride and suitable thiolic compounds is described. The derivatives were characterised by potentiometric analyses and 13C-NMR spectra. The products obtained show a great solubility in water, but also in ethanol and methanol and act as complexing agents for many bivalent metallic cations. These derivatives are probably biodegradable and non toxic. |
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