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Structure-function relations of carbohydrates by neoglycolipid arrays
Authors:Gang-Liang Huang  Hua-Liang Huang  Hou-Cheng Zhang  Peng-George Wang
Institution:(1) School of Life Science, Shandong, University, Jinan City, 250100 Jinan, China;(2) School of Chemistry, Xiangtan, University, 411105 Xiangtan City, China
Abstract:The work presented herein is a new noncovalent glycoarray assembly method for microplates created by simply mixing together a carbohydrate and a teradecylamine. α-d-Mannopyranoside, α-d-glucopyranoside, and α-d-galactopyranoside were utilized in model studies and product formations were detected by lectin binding. The method can be extended to study the steric hindrance effect of carbohydrate-protein interactions, namely the structure-function relations of carbohydrates. These authors contributed equally to this work.
Keywords:Glycoarray  neoglycolipid  structure-function relations
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