新疆古代居民的遗传结构分析

新疆维吾尔自治区地处于古代东西方经贸、文化交流的大通道丝绸之路的中心地段 .这一地区的人群在人类学上呈现出东亚与欧洲之间的混合特征 .由于这一地区处于人际交叉地带 ,地理位置上无天然的屏障 ,且在历史上经历过多次的迁徙、混合和战争 ,仅仅从现代人的遗传特征和核酸序列来推测古代中亚各民族的起源和迁徙必然会受到这些历史过程的影响 ,而使用古 DNA来研究西域古代群体的遗传结构无疑是对这一问题的近距离考察 .本文通过对所采集的样本中的线粒体 DNA进行序列分析 ,为了解新疆各民族的起源、发展、融合与分化的历史轨迹提供了必…

Analysis of Genetical Structure of the Ancient Xinjiang Population

MtDNA was successfully extracted from 31 ancient individual bones at the tombs of Turfan basin and Lubunouer. Through four overlapping primers, we got 30 nucleotide sequences of 363 bp length. Intermediate nucleotide diversity, and genetic distances, as well as mean pairwise variance, are compatible with ancient Turfan mtDNA pool being an admixture of eastern Asian and European lineages. Such phenomenon shows that prior to the time of ancient Turfan, an ancient mingling of Euro-Asian population in Turfan basin had existed. The ancient Luobunuoer was the relic of Xinjiang that was found in the earliest time and at the farthest orient. The mtDNA sequences of ancient Luobunuoer are consisted by European lineage completely, no trace of mixture with Asian lineage. From nucleotide diversity, and genetic distances and mean pairwise variance, it has close relationship with European populations.