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Amoxicillin removal from aqueous solutions using hollow fibre supported liquid membrane: kinetic study
Authors:Teerapon Pirom  Thidarat Wongsawa  Thanaporn Wannachod  Niti Sunsandee  Ura Pancharoen  Soorathep Kheawhom
Affiliation:1.Department of Chemical Engineering, Faculty of Engineering,Chulalongkorn University,Bangkok,Thailand;2.Government Pharmaceutical Organization,Bangkok,Thailand
Abstract:Amoxicillin was removed from aqueous solutions using hollow fibre supported liquid membrane system (HFSLM). After evaluation of the influencing variables, the highest permeation coefficient of amoxicillin reached 2.778 × 10?4 ms?1 when the length of hollow fibres was 15 cm and the operating time was 60 min. Then, the reaction flux models of extraction and stripping were calculated. Thereafter, the modelling results were compared with the experimental data at standard deviations of 2.07 and 3.19%. In the comparison of carrier and diluent, the best conditions were achieved when Aliquat 336 and 1-Decanol were used. Results showed that amoxicillin extraction and stripping were of first and zero reaction orders; their reaction rate constants were 0.0344 min?1 and 0.0445 mg/L·min, respectively.
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