A Halogen‐Bond Donor Catalyst for Templated Macrocyclization |
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Authors: | Kvin Guillier Elsa Caytan Vincent Dorcet Florence Mongin lise Dumont Floris Chevallier |
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Institution: | Kévin Guillier,Elsa Caytan,Vincent Dorcet,Florence Mongin,Élise Dumont,Floris Chevallier |
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Abstract: | A halogen‐bond templated 1:1 macrocyclization in solution is reported. Tetra(iodoperfluorophenyl) ethers were used as halogen‐bonded exotemplates in a substoichiometric amount (5 mol %). Pyridine‐containing macrocyclic architectures were formed by ruthenium‐catalyzed tandem metathesis/transfer hydrogenation sequence using sodium borohydride and methanol as non‐dihydrogen hydrogen source. The halogen‐bonded stabilization energies were analyzed relying on density functional theory. |
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Keywords: | Halogenbrü cken Metathese Organokatalyse Templatsynthese Wasserstofftransfer |
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