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Water‐soluble AIE‐Active Fluorescent Organic Nanoparticles: Design,Preparation and Application for Specific Detection of Cysteine over Homocysteine and Glutathione in Living Cells
Authors:Zhang‐wei Ning  Song‐ze Wu  Guang‐jian Liu  Yan‐ming Ji  Li‐yan Jia  Xiao‐xiao Niu  Rong‐fang Ma  Yuan Zhang  Guo‐wen Xing
Abstract:Water‐soluble ratiometric AIE‐active fluorescent organic nanoparticles 2OA‐FON for the specific sensing of cysteine over other biothiols are reported. The obtained amphiphilic probe included olefin aldehyde as recognizing unit, tetraphenylethylene as fluorescence reporter and lactose moiety as a hydrophilic group. This work provides a general design strategy based on the introduction of a sugar moiety into a hydrophobic AIEgen to develop ratiometric water‐soluble fluorescent organic nanoparticles.
Keywords:aggregation-induced emission  biothiols  cysteine  nanoparticles  tetraphenylethylene
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