Copper‐Catalyzed Enantioselective Allylboration of Alkynes: Synthesis of Highly Versatile Multifunctional Building Blocks |
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Authors: | Eva Rivera‐Chao Maider Mitxelena Jesús A Varela Martín Faans‐Mastral |
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Institution: | Eva Rivera‐Chao,Maider Mitxelena,Jesús A. Varela,Martín Fañanás‐Mastral |
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Abstract: | The first copper‐catalyzed enantioselective allylboration of alkynes is reported. The method employs a multitasking chiral NHC‐Cu catalyst and provides access to densely functionalized molecules from simple starting materials with excellent levels of chemo‐, regio‐, and enantioselectivity. These multifunctional products display highly versatile reactivity as shown by the synthesis of a variety of non‐racemic molecular scaffolds. DFT calculations were conducted to gain insight into the high selectivity levels of this catalytic process. |
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Keywords: | Asymmetrische Katalyse Bor Diversitä tsorientierte Synthese Kupfer Mehrkomponentenreaktionen |
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