Synthesis of α‐fluoro‐β‐trifluoromethyl alka‐2,4‐dienes

The palladium/copper(I) iodide cocatalyzed coupling reaction of (Z)‐α‐fluoro‐β‐trifluoromethylstannanes ( 1 ) with vinyl iodides ( 2 ) has been explored giving substituted α‐fluoro‐β‐trifluoromethyl dienes ( 3 ) in 33–95% yields. In studies we have conducted so far, a larger number of the configurations of the products remained unchanged (cases 3a, 3e–h ), though in several cases (cases 3b–d ) two configurations of the products were obtained. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:208–211, 2007; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20284