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Conformational analysis of 12,12,21,21-tetradeuterio-1,4-dioxa-[4.3.3](1,3,5)Cyclophane
Affiliation:1. Department of Chemistry, Faculty of Science and Engineering, Saga University, Honjo-cho 1, Saga 840, Japan;1. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;2. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;1. Chongqing Research Center for Pharmaceutical Engineering, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), College of Pharmacy, Chongqing Medical University, Chongqing, 400016, PR China;2. Chongqing Key Laboratory of Green Synthesis and Applications, College of Chemistry, Chongqing Normal University, Chongqing, 401331, PR China;3. Department of Clinical Laboratory, University-Town Hospital of Chongqing Medical University, Chongqing, 401331, PR China;1. Neuroproteomics, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany;2. Institut für Chemie und Biochemie, Freie Universität Berlin, Berlin, Germany;3. Leibniz-Institut für Molekulare Pharmakologie, Berlin, Germany
Abstract:All possible three conformers (chair-chair, chair-boat, and boat-boat) of the title compound were detected by 1H NMR spectrum below 223K(−50°C).
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