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Synthesis of 3,3-difluoro-2-azetidinones and 2,3-dideoxy-2,2-difluoro-3-amino-sugars through the reformatsky reaction of difluoroacetate with imine
Institution:1. Tokyo College of Pharmacy, 1432-1 Horinouchi, Hachioji, Tokyo 192-03, Japan;2. Faculty of Pharmaceutical Science, The University of Tokyo, Bunkyo-ku, Tokyo 102, Japan;1. School of Pharmacy, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou 213164, China;2. Department of Chemistry, University of New Hampshire, 23 Academic Way, Durham, NH 03824, USA;1. Junior Research Group Synthetic Microbiology, Friedrich Schiller University at the Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute, Beutenbergstr.11a, 07745 Jena, Germany;1. China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China;2. College of Chemistry, Tianjin Key Laboratory of Structure and Performance for Functional Molecules, Tianjin Normal University, Tianjin 300387, China;1. School of Chemistry and Chemical Engineering, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, PR China;2. Zhejiang Sci-Tech University Shengzhou Innovation Research Institute, Shengzhou 312400, PR China;3. Zhejiang Anglikang Pharmaceutical CO. LTD, Shengzhou 312400, PR China
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