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Application of the NG-(2,2,5,7,8-pentamethylchroman-6-sulphonyl) derivative of FMOC-arginine to peptide synthesis
Affiliation:1. Applied Physics Laboratory, Physics Department, Faculty of Science and Technology, Tangier, Morocco;2. Laboratory of Science and Advanced Technology, Physics Department, Polydisciplinary Faculty, Larache, Morocco;1. N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, 9 Ac. Lavrentiev Avenue, Novosibirsk, 630090, Russia;2. Novosibirsk State University, 2 Pirogova Str., Novosibirsk, 630090, Russia;1. Research Center for Nanocatalysts, Korea Research Institute of Chemical Technology (KRICT), 141 Gajeong-Ro, Yuesong, Daejeon 305-600, Republic of Korea;2. Center for Convergent Chemical Process, Korea Research Institute of Chemical Technology (KRICT), 141 Gajeong-ro, Yuseong-gu, Daejeon 305-600, Republic of Korea;3. Department of Chemistry, Sungkyunkwan University, Suwon 440-476, Republic of Korea;1. Departamento de Química Inorgánica e Ingeniería Química, Instituto Universitario de Química Fina y Nanoquímica, Universidad de Córdoba, Edificio Marie Curie, Campus de Rabanales, 14071, Córdoba, Spain;2. LSQM—Laboratory of Chemical Synthesis of Materials – Department of Materials Engineering, Federal University of Rio Grande do Norte, P.O. Box 1524, 59078-900, Natal, RN, Brazil;1. State Key Laboratory of Fine Chemicals, Dalian University of Technology, Panjin, 124221, Liaoning, China;2. Hubei Provincial Key Laboratory of Green Materials for Light Industry, Collaborative Innovation Center of Green Light-weight Materials and Processing, Hubei University of Technology, Wuhan, 430068, Hubei, China
Abstract:The trifluoroacetic acid labile pentamethylchromanylsulphonyl protecting group for the guanidino group of arginine has been used in conjunction with the base-labile Fmoc Nα protecting group for the synthesis of arginine-containing peptides.
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