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Eight-membered ring templates for stereoselective radical cyclizations
Affiliation:1. Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa Av. Rovisco Pais, 1049-001 Lisboa, Portugal;2. Department of Chemistry, Faculty of Science, Helwan University, Ain Helwan, 11795 Cairo, Egypt;1. School of Chemistry, Trinity Biomedical Science Institute, Trinity College Dublin, 152-160, Pearse St., Dublin 2, Ireland;2. School of Biochemistry and Immunology, Trinity Biomedical Science Institute, Trinity College Dublin, 152-160, Pearse St., Dublin 2, Ireland;1. College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Dushu Lake Campus, Suzhou 215123, China;2. XStruct, Department of Chemistry, Ghent University, Krijgslaan 281-S3, B-9000 Ghent, Belgium
Abstract:The radical cyclization of suitably disubstituted cyclooctadienes and cyclooctenes leads to the formation of trans-bicyclo[6.3.0]undecane ring systems with exceedingly high levels of stereochemical control.
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