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A combined chemical and enzymatic procedure for the synthesis of 1-deoxynojirimycin and 1-deoxymannojirimycin
Affiliation:1. Academy of Scientific and Innovative Research, New Delhi, India;2. Organic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India;3. Centre for Nuclear Magnetic Resonance and Structural Chemistry Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India;1. Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-5791, Japan;2. Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-5791, Japan;3. School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-5791, Japan;4. Hall-Atwater Laboratories of Chemistry, Wesleyan University, Middletown, CT 06459-0180, USA;1. Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada;2. Centre for Catalysis Research and Innovation, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada;3. Département de Chimie, Université de Montréal, Montréal, Québec H3T 1J4, Canada;4. PROTEO Network, Université Laval, Québec, Québec G1V 0A6, Canada;5. Center for Green Chemistry and Catalysis, Montréal, Québec H3A 0B8, Canada;1. Chemical and Biological Engineering Department, Colorado School of Mines, Golden, Colorado 80401;2. Department of Psychological and Brain Sciences and Dartmouth Brain Imaging Center, Dartmouth College, Hanover, New Hampshire 03755;3. Department of Chemistry, Colorado School of Mines, Golden, Colorado 80401;1. Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, 4-101 Koyamacho-minami, Tottori City, 680-8552 Tottori, Japan;2. Center for Research on Green Sustainable Chemistry, Faculty of Engineering, Tottori University, Japan
Abstract:1-Deoxynojirimycin and 1-deoxymannojirimycin have been prepared via fructose diphosphate aldolase catalyzed condensation followed by catalytic intramolecular reductive amination.
Keywords:
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