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Enantioselective total synthesis of the pumiliotoxin a alkaloids via reductive iminium ion-alkyne cyclizations. Total synthesis of (+)-pumiliotoxin a
Affiliation:1. SRM Research Institute, SRM Institute of Science and Technology, Kattankulathur, Chennai, Tamil Nadu 603203, India;2. Kalaslingam Academy of Research and Education, Krishnan Kovil, Tamil Nadu 626126, India
Abstract:A highly practical new route for the enantioselective synthesis of the pumiliotoxin A alkaloids in which the title reaction is a key step is disclosed.
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