Condensation of Isatoic Anhydride with Hetarylguanidines |
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Authors: | Shikhaliev Kh. S. Kryl'skii D. V. Shestakov A. S. Falaleev A. V. |
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Affiliation: | (1) Voronezh State University, Voronezh, Russia |
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Abstract: | Condensation of isatoic anhydride with 4-methylquinazolin-2-yl-, 2-benzoxazolyl-, 2-benzothiazolyl-, and 4,6-dimethylpyrimidin-2-ylguanidines leads to the corresponding 2-hetarylamino-4-hydroxyquinazolines as a result of cyclization of intermediate anthranilic acid hetarylguanidides. These intermediates can be isolated as individual compounds. |
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