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Condensation of Isatoic Anhydride with Hetarylguanidines
Authors:Shikhaliev  Kh. S.  Kryl'skii  D. V.  Shestakov  A. S.  Falaleev  A. V.
Affiliation:(1) Voronezh State University, Voronezh, Russia
Abstract:Condensation of isatoic anhydride with 4-methylquinazolin-2-yl-, 2-benzoxazolyl-, 2-benzothiazolyl-, and 4,6-dimethylpyrimidin-2-ylguanidines leads to the corresponding 2-hetarylamino-4-hydroxyquinazolines as a result of cyclization of intermediate anthranilic acid hetarylguanidides. These intermediates can be isolated as individual compounds.
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