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89Zr and 177Lu labeling of anti-DR5 monoclonal antibody for colorectal cancer targeting PET-imaging and radiotherapy |
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| Authors: | Yang Yuchuan Wang Jing Liu Wei Deng Hao Zhao Peng Liao Wei Wang Guanquan Wei Hongyuan Zhuo Liangang Yang Xia |
| Affiliation: | 1.Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang, 621900, People’s Republic of China ;2.Department of Nuclear Medicine, The Affiliated Hospital Southwest of Medical University, Luzhou, 646000, People’s Republic of China ;3.Collaborative Innovation Center of Radiation Medicine of Jiangsu, Higher Education Institutions, Suzhou, 215123, People’s Republic of China ;4.Key Laboratory of Nuclear Medicine and Molecular Imaging of Sichuan Province, Mianyang, 621999, People’s Republic of China ; |
| Abstract: | Journal of Radioanalytical and Nuclear Chemistry - Death receptor 5 (DR5) is overexpressed in many tumors. Combination of the anti-DR5 antibody with radionuclides such as lutetium-177 (177Lu) could... |
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