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Amphiphilic star-block copolymers and supramolecular transformation of nanogel-like micelles to nanovesicles
Authors:Zhu Jing-Ling  Liu Kerh Li  Zhang Zhongxing  Zhang Xian-Zheng  Li Jun
Institution:Department of Bioengineering, Faculty of Engineering, National University of Singapore, 7 Engineering Drive 1, Singapore 117574, Singapore.
Abstract:Amphiphilic star-block copolymers based on poly(3-hydroxybutyrate) with adamantyl end-functionalization were synthesized via anionic ring-opening polymerization and alkyne-azide "Click Chemistry" coupling. In aqueous medium, the copolymers self-assembled into nanogel-like large compound micelles, and transformed into vesicular nanostructures under the direction of host-guest interaction between the adamantyl end and dimethyl-β-cyclodextrin.
Keywords:
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