Ga-labeling of immunoglobulin G with high specific radioactivity |
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| Authors: | T Furukawa Y Fujibayashi M Fukunaga A Yokoyama |
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| Institution: | Department of Health Chemistry, Kansai Medical University, Osaka, Japan. |
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| Abstract: | To obtain radiogallium labeled immunoglobulin G with a high specific radioactivity for in vitro use, a 67Ga source was purified by extraction from 67Ga-gallium citrate with butyl acetate, and a 67Ga-labeling solution was produced. This solution was then used to label a deferoxamine-immunoglobulin G conjugate. Both a very high specific radioactivity (872 +/- 56 MBq/mg) and a high labeling efficiency (94.0%) were achieved. |
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