Evolutionary Approaches to DNA Sequencing with Errors

In the paper, two evolutionary approaches to the general DNA sequencing problem, assuming both negative and positive errors in the spectrum, are compared. The older of them is based on the idea of genetic approach and is enhanced by a greedy algorithm. The newly proposed algorithm combines the tabu search and the scatter search methods. After conducting experiments with random and coding DNA sequences, our results suggest that the tabu and scatter search algorithm finds solutions of higher quality and more reliably than the genetic algorithm.