Two new bioactive sesquiterpenes from the soft coral Sinularia sp |
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| Authors: | Zhang Guang-Wen Ma Xiang-Quan Su Jing-Yu Zhang Kun Kurihara Hiroshi Yao Xin-Sheng Zeng Long-Mei |
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| Institution: | School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China. |
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| Abstract: | Two new sesquiterpenes, 1S*, 4R*, 5S*, 6R*, 7S*, 10S*-1(5), 6(7)-diepoxy-4-guaiol (1) and 1S*, 4S*, 5S*, 10R*-4,10-guaianediol (2) have been isolated from the ethyl acetate soluble portion of the soft coral Sinularia sp., and their stereostructure were determined by spectroscopic methods and by X-ray single crystal analysis. Both compounds showed antioxidant and cytotoxic activities. |
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