(P,C) Cyclometalated Gold(III) Complexes: Highly Active Catalysts for the Hydroarylation of Alkynes |
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| Authors: | Charlie Blons Sonia Mallet‐Ladeira Dr Abderrahmane Amgoune Dr Didier Bourissou |
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| Institution: | 1. http://lhfa.cnrs.fr/index.php/equipes/lbpb/accueil‐lbpb;2. CNRS/Université Paul Sabatier, Laboratoire Hétérochimie Fondamentale et Appliquée (LHFA, UMR 5069), Toulouse Cedex 09, France;3. Institut de Chimie de Toulouse (FR 2599), Toulouse Cedex 09, France |
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| Abstract: | The first catalytic application of well‐defined (P,C) cyclometalated gold(III) complexes is reported. The bench‐stable bis(trifluoroacetyl) complexes 2 a , b perform very well in the intermolecular hydroarylation of alkynes. The reaction is broad in scope, it proceeds within few hours at 25 °C at catalytic loadings of 0.1–5 mol %. The electron‐rich arene adds across the C≡C bond with complete regio‐ and stereo‐selectivity. The significance of well‐defined gold(III) complexes and ligand design are highlighted in a powerful but challenging catalytic transformation. |
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| Keywords: | alkynes gold(III) homogeneous catalysis hydroarylation P-based ligands |
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