Enantioselective Construction of Tertiary Boronic Esters by Conjunctive Cross‐Coupling |
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| Authors: | Jesse A. Myhill Liang Zhang Gabriel J. Lovinger Prof. James P. Morken |
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| Affiliation: | Department of Chemistry, Boston College, Chestnut Hill, MA, USA |
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| Abstract: | Catalytic enantioselective conjunctive cross‐coupling has been developed to construct tertiary alkylboronic esters. These reactions occur with good yield and enantioselectivity for a range of substrates. Mechanistic experiments reveal aspects of the catalytic cycle that allow hindered substrates to react without significant complicating side reactions. |
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| Keywords: | asymmetric catalysis boron cross coupling quaternary centers |
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