Regiospecific N‐Arylation of Aliphatic Amines under Mild and Metal‐Free Reaction Conditions |
| |
Authors: | Dr. Nibadita Purkait Gabriella Kervefors Erika Linde Prof. Berit Olofsson |
| |
Affiliation: | Department of Organic Chemistry, Arrhenius Laboratory, Stockholm, Sweden |
| |
Abstract: | A transition metal‐free N‐arylation of primary and secondary amines with diaryliodonium salts is presented. Both acyclic and cyclic amines are well tolerated, providing a large set of N‐alkyl anilines. The methodology is unprecedented among metal‐free methods in terms of amine scope, the ability to transfer both electron‐withdrawing and electron‐donating aryl groups, and efficient use of resources, as excess substrate or reagents are not required. |
| |
Keywords: | anilines arylamines diaryliodonium salts hypervalent iodine metal-free reactions |
|
|