Selective extraction of flavonoids from Ginkgo biloba leaves using human serum albumin functionalized magnetic nanoparticles

In a novel procedure, human serum albumin functionalized magnetic nanoparticles (HSA-MNPs) were used to selectively extract nine flavonoids in the extract of Ginkgo biloba leaves. The chemical structures of those flavonoids were characterized with high performance liquid chromatography coupled with mass spectrometry (HPLC–MS). The selective extraction with HSA-MNPs coupled with structural elucidation with HPLC–MS shows powerful potential for analysis of bioactive components in traditional Chinese medicines.