毛细管电泳质谱联用技术及其应用

本文介绍了用于毛细管电泳质谱联用仪器的多种接口技术，描述了ＣＺＥ，ＣＩＥＦ，ＣＧＥ，ＭＥＫＣ和ＣＩＴＰ等毛细管电泳技术和四极质谱，离子阱质谱，傅 叶变换离子回旋共振质谱，飞行时间质谱，磁质谱，解吸质谱等联用的现状及发展前景，对近年来ＣＥ－ＭＳ在酶解产物。蛋白质和肽，核苷酸，药物及代谢产物等领域中的应用作了详细述评。

Capillary Electrophoresis Mass Spectrometry and Its Application

In this paper, several kinds of CE MS interface including ESI, ISP, APCI, FAB, PD and MALDI are introduced. The present situation and the prospect of capillary electrophoresis techniques such as CZE, CITP, CGE, MEKC and CITP, coupling with mass spectrometry including SSQ MS, TSQ MS, FTICR MS, TOF MS, ICP MS and magnetic sector MS, were described. The applications of CE MS to analyse protein and peptide, tryptic digests, nucleotide,drug and its metabolites were reviewed.