AuCl3-Catalyzed Ring-Closing Carbonyl–Olefin Metathesis |
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| Authors: | Prof Dr Rui Wang Yi Chen Mao Shu Wenwen Zhao Maoling Tao Chao Du Xiaoya Fu Prof Dr Ao Li Prof Dr Zhihua Lin |
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| Institution: | 1. School of Pharmacy & Bioengineering, Chongqing University of Technology, 69 Red Avenue, Chongqing, 400054 China;2. School of Pharmacy & Bioengineering, Chongqing University of Technology, 69 Red Avenue, Chongqing, 400054 China
These authors contributed equally to this work |
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| Abstract: | Compared with the ripeness of olefin metathesis, exploration of the construction of carbon–carbon double bonds through the catalytic carbonyl–olefin metathesis reaction remains stagnant and has received scant attention. Herein, a highly efficient AuCl3-catalyzed intramolecular ring-closing carbonyl–olefin metathesis reaction is described. This method features easily accessible starting materials, simple operation, good functional-group tolerance and short reaction times, and provides the target cyclopentenes, polycycles, benzocarbocycles, and N-heterocycle derivatives in good to excellent yields. |
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| Keywords: | benzocarbocycles gold catalysis heterocycles metathesis organic synthesis |
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