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LR-selHSQMBC: Simultaneous Detection and Quantification of Very Weak Long-Range Heteronuclear NMR Correlations |
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| Authors: | Kumar Motiram-Corral Dr. Alexandre A. Souza Dr. Josep Saurí Dr. Pau Nolis Dr. Teodor Parella |
| Affiliation: | 1. Servei de Ressonància Magnètica Nuclear, Universitat Autònoma de Barcelona, E-08193 Bellaterra Barcelona (Catalonia, Spain;2. Departamento de Química, Universidade Federal de Piauí, 64049-550 Teresina„ PI, Brazil;3. Structure Elucidation Group, Analytical Research & Development, Merck & Co., Inc., 33 Av. Louis Pasteur, Boston, MA, 02215 USA |
| Abstract: | The optimum detection and accurate measurement of longer-range (4J and higher) heteronuclear NMR correlations is described. The magnitude and/or the sign of a wide range of large and small long-range couplings can be simultaneously determined for protonated and non-protonated 13C and 15N nuclei using the LR-selHSQMBC experiment. |
| Keywords: | heteronuclear coupling constants long-range heteronuclear connectivities NMR spectroscopy proton-deficient molecules structure elucidation time-sharing NMR |