| Affiliation: | 1. Department of Chemistry, University of Michigan, Ann Arbor, MI, 48108 USA;2. Phantom-g, CICECO-Aveiro Institute of Materials, Department of Physics, University of Aveiro, Campus de Santiago, Aveiro, Portugal Faculty of Chemistry, University of Wroclaw, Wroclaw, Poland;3. Centre de Biophysique Moléculaire, CNRS, UPR 4301, 45071 Orléans Cedex 2, France;4. Phantom-g, CICECO-Aveiro Institute of Materials, Department of Physics, University of Aveiro, Campus de Santiago, Aveiro, Portugal |
| Abstract: | Nanothermometry is the study of temperature at the submicron scale with a broad range of potential applications, such as cellular studies or electronics. Molecular luminescent-based nanothermometers offer a non-contact means to record these temperatures with high spatial resolution and thermal sensitivity. A luminescent-based molecular thermometer comprised of visible-emitting Ga3+/Tb3+ and Ga3+/Sm3+ metallacrowns (MCs) achieved remarkable relative thermal sensitivity associated with very low temperature uncertainty of Sr=1.9 % K−1 and δT<0.045 K, respectively, at 328 K, as an aqueous suspension of polystyrene nanobeads loaded with the corresponding MCs. To date, they are the ratiometric molecular nanothermometers offering the highest level of sensitivity in the physiologically relevant temperature range. |
