| Abstract: | The reductive amination ofl-menthol with aliphatic nitriles has been studied. A probable scheme of the mechanism of the reaction has been put forward and the stereochemical composition of its products has been determined. It has been established with the aid of the13C NMR method that the reaction forms a mixture of isomeric optically-active N-alkylmenthyl-, -neomenthyl-, -isomenthyl-, and-neoisomenthyl-amines in a ratio of 54:24:17:5. The absolute configurations of the amines obtained have been determined. |
