|
|||||
|
|
Separation of enantiomers on bovine serum albumin coated zirconia in reversed-phase liquid chromatography |
|
| Authors: | J. H. Park J. K. Ryu J. K. Park C. V. McNeff P. W. Carr |
| Affiliation: | (1) Department of Chemistry, Yeungnam University, 712-749 Kyongsan, Korea;(2) Zirchrom Separations, Inc., 55303 Anoka, MN, USA;(3) Department of Chemistry, University of Minnesota, 55455 Minneapolis, MN, USA |
| Abstract: | Summary Zirconia is known to be one of the best materials for the chromatographic support due to its excellent chemical, thermal and mechanical stability. In this work we report preparation and use of bovine serum albumin (BSA)-immobilized zirconia as a chiral stationary phase for separation of some enantiomers in reversed-phase liquid chromatography. The BSA-zirconia showed good enantioselectivity for some of the enantiomers studied and could be used for RPLC separations in mobile phases of alkaline pH. |
| Keywords: | Column liquid chromatography Bovine serum albumin Zirconia Stationary phase Chiral separation |
| 本文献已被 SpringerLink 等数据库收录！ | |