Electrokinetics in antimicrobial resistance analysis: A review |
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| Authors: | Junyan Zhang Mengqi Li Runxin Xu Suman Kapur Antonio Bombard Yongxin Song |
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| Institution: | 1. Department of Marine Engineering, Dalian Maritime University, Dalian, P. R. China;2. Department of Navigation, Dalian Maritime University, Dalian, P. R. China;3. Department of Biological Sciences, Birla Institute of Technology and Science, Pilani, Hyderabad Campus, Hyderabad, Telangana, India;4. Physics and Chemistry Institute, Federal University of Itajubá, Itajubá, Brazil |
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| Abstract: | Infections caused by antimicrobial resistance are a serious problem in the world. Currently, commercial devices for antimicrobial susceptibility testing and resistant bacteria identification are time-consuming. There is an urgent need to develop fast and accurate methods, especially in the process of sample pretreatment. Electrokinetic (EK) is a family of electric-field-based kinetic phenomena of fluid or embedded objects, and EK applications have been found in various fields. In this paper, EK bacteria manipulation, including enrichment and separation, is reviewed. Focus is given to the rapid electric-based minimum inhibitory concentration measurement. The future directions and major challenges in this field are also outlined. |
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| Keywords: | antimicrobial susceptibility testing bacteria electrokinetics manipulation |
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