Toward on-chip X-ray analysis |
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Authors: | Greaves Eduardo D Manz Andreas |
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Institution: | Universidad Simón Bolívar, Apartado 89000, Caracas 1080A, Venezuela. egreaves@usb.ve |
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Abstract: | The possibility of performing chemical analysis and structure determinations with the use of X-rays in a microfluidic chip environment is explored. Externally generated radiation, radioisotope irradiation and on-chip generated X-rays were considered as excitation means for the performance of sample analysis with the techniques of X-ray fluorescence and diffraction. The absorption properties of chip-building materials by different radiation sources are reviewed and data on absorption coefficients calculated, upon which recommendations for optimisations with the use of various X-ray sources may be made. The capabilities and limitations of on-chip X-ray analysis are placed in perspective by preliminary experimental results of diffraction, fluorescence and on-chip X-ray generation experiments. |
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