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| 国内外应用天然药物的有效部位、单体防治肝纤维化的研究进展 | |
| 引用本文： | 高鹏飞,刘卫红,李凤贤,李辉,杜一民,刘蜻蜻,巫秀美,赵昱,刘光明.国内外应用天然药物的有效部位、单体防治肝纤维化的研究进展[J].大理学院学报,2012,11(6):5-11. |
| 作者姓名： | 高鹏飞 刘卫红 李凤贤 李辉 杜一民 刘蜻蜻 巫秀美 赵昱 刘光明 |
| 作者单位： | 1. 大理学院药学与化学学院,云南大理,671000 2. 大理学院农学与生物科学学院,云南大理,671003 3. 大理学院附属医院,云南大理,671000 |
| 基金项目： | 国家自然科学基金资助项目，云南省基础应用基金资助项目，云南省高层次人才培引工程项目，云南省科技厅重点产业创新工程(中药现代化科技产业云南基地建设)项目 |
| 摘 要： | 目的：综述近年来用于治疗肝纤维化天然药物的有效部位及单体活性成分的研究进展。方法：对34种天然药物的生物碱类、总黄酮和总酚酸类、单体酚酸类、萜类及其苷和甾醇类、木脂素类、氨基酸/多肽和杂环类、多糖类、香豆素类进行分析。结果：已报道的34种天然药物对肝纤维化均具有一定的治疗效果。结论：对未来治疗肝纤维化的新药研发方向进行展望。 |
| 关 键 词： | 天然药物 有效部位 单体活性成分 肝纤维化 治疗肝纤维化 新药研发 |
Research Progress on Active Fractions and Monomers from Natural Drugs in the Treatment of Liver Fibrosis |
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| GAO Pengfei,LIU Weihong,LI Fengxian,LI Hui,DU Yimin,LIU Qingqing,WU Xiumei,ZHAO Yu,LIU Guangming.Research Progress on Active Fractions and Monomers from Natural Drugs in the Treatment of Liver Fibrosis[J].Journal of Dali University,2012,11(6):5-11. | |
| Authors: | GAO Pengfei LIU Weihong LI Fengxian LI Hui DU Yimin LIU Qingqing WU Xiumei ZHAO Yu LIU Guangming |
| Institution: | 1 * (1.College of Pharmacy and Chemistry,Dali University,Dali,Yunnan 671000,China; 2.College of Agriculture and Biology Science,Dali University,Dali,Yunnan 671003,China; 3.Affliated Hospital of Dali University,Dali,Yunnan 671000,China) |
| Abstract: | Objective: To review the recent research progress domestic and abroad of the utilization of natural drugs for the treatment of liver fibrosis.Methods:Thirty-four reported natural drugs were summarized and classified into alkaloids,total flavonoids and total phenolics,single phenolics,terpenoids and its glycosides and steroids,lignanoids,amino acids and heterocyclic,polypeptides/glycopeptides and coumarins.Results: Thirty-four reported natural drugs all have certain effect for the treatment of liver fibrosis.Conclusion: The prospect of the research and development of the new natural drugs against liver fibrosis were discussed. |
| Keywords: | natural drugs active fractions active monomer liver fibrosis anti-liver fibrosis new drug research and development |
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