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Microwave-assisted Synthesis of Pyrazolo[4,3-f]quinolin-7-one Derivatives via Multi-component Reactions
Authors:PENG Juhua  HAO Wenjuan  WANG Xiang  TU Shujiang  MA Ning  ZHANG Ge
Affiliation:1. Lianyungang Teachers' College, Lianyungang, Jiangsu 222006, China;2. College of Chemistry and Chemical Engineering, Xuzhou Normal University, Xuzhou, Jiangsu 221116, China;3. Tel. & Fax: 0086‐0516‐83403165
Abstract:A series of new pyrazolo[4,3‐f]quinolin‐7‐one derivatives were synthesized by multi‐component reactions of equimolar amount of aromatic aldehydes with 2,2‐dimethyl‐1,3‐dioxane‐4,6‐dione and 1H‐indazol‐5‐amine in ethylene glycol without catalyst under microwave irradiation. This one‐pot protocol has the advantage of good yields, simple workup procedure and shorter reaction time.
Keywords:pyrazolo[4,3‐f]quinolin‐7‐one  microwave irradiation  multi‐component reaction
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