Asymmetric catalysis LVI. Enantioselective hydrosilylation of acetophenone with a rhodium/picolineoxazoline catalyst 1:1

The direction of optical induction is inverted in going from pyridineoxazoline 1 to picolineoxazoline 2 as cocatalyst in the Rh-catalyzed asymmetric hydrosilylation of acetophenone with diphenylsilane. In the case of ligand 2, a 1.2-fold excess of the ligand is sufficient to achieve the highest enantiomeric excess.