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Study of acoustic nonlinearity parameter imaging methods in reflection mode for biological tissues
Authors:Gong Xiufen  Zhang Dong  Liu Jiehui  Wang Huanlei  Yan Yongsheng  Xu Xiaochen
Institution:State Key Lab of Modern Acoustics, Institute of Acoustics, Nanjing University, Nanjing 210093, China. dzhang@nju.edu.cn
Abstract:Three novel methods for acoustic nonlinearity parameter B/A imaging in reflection mode are developed in this paper. They are: (1) the acoustic nonlinearity parameter B/A tomography by detecting reflective second harmonic wave, (2) the B/A tomography in reflection mode via the measurement of the difference frequency wave generated by a parametric array, and (3) the C-scan imaging of B/A via the measurement of the echo second-harmonic signal. A theoretical analysis and the experimental imaging of normal and pathological biological tissues by using these methods are also present and discussed. Results show that using the acoustic nonlinearity parameter imaging we can more easily distinguish the diseased tissue from the normal one than using the linear acoustic parameters.
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