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An expedient synthesis of (+)-quinolactacin A2
Authors:Su-Jin Park  Won-Gon Kim
Affiliation:a Bio-Organic Science Division, Korea Research Institute of Chemical Technology, PO Box 107, Yusong, Taejon 305-600, Korea
b National Research Laboratory of Antioxidant, Korea Research Institute of Bioscience and Biotechnology, PO Box 115, Yusong, Taejon 305-600, Korea
Abstract:An expedient synthesis of quinolactacin A2 from N-methylisatoic anhydride and N-Boc-(2S,3S)-isoleucine has been achieved. The key step involves the Friedländer-type annulation of isatoic anhydride and β-ketoester derived from isoleucine.
Keywords:Isatoic anhydride   β-ketoester   Friedlä  nder-type annulation   (+)-Quinolactacin A2
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