Zinc-catalyzed Williamson ether synthesis in the absence of base |
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Authors: | Satya Paul Monika Gupta |
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Affiliation: | Department of Chemistry, University of Jammu, Jammu 180 006, India |
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Abstract: | Zinc powder was found to be a highly efficient catalyst for the synthesis of aromatic ethers using microwave heating in the presence of N,N-dimethylformamide as well as under stirring in an oil-bath using tetrahydrofuran as solvent without any inorganic base. This method can be used for selective mono-, di- or tri-O-alkylations. |
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Keywords: | Williamson reaction Aromatic ethers Zinc powder Microwave activation Oil-bath heating |
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