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A mild procedure for the oxidative cleavage of substituted indoles catalyzed by plant cell cultures
Authors:Masumi Takemoto  Yasutaka Iwakiri  Yuki Suzuki  Kiyoshi Tanaka
Affiliation:School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan
Abstract:We have developed a novel procedure for the oxidative cleavage of indole carbon double bonds in the presence of H2O2 using plant cell cultures as a catalytic system. The oxidative procedure has some advantages, such as mild reactions, good yields, easy work-up and safety.
Keywords:Oxidative cleavage reactions   Enamines   Indoles   Carbazoles   Catalysts   Enzymes and enzyme reaction
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