Synthesis of a cryptand with tetrahedral connectivity using multiple ring-closing olefin metathesis |
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| Authors: | Shiyue Fang |
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| Affiliation: | Department of Medicinal Chemistry and Molecular Pharmacology, 201 S University Street, Purdue University, West Lafayette, IN 47907, USA Walther Cancer Institute, Indianapolis, IN 46208, USA |
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| Abstract: | By connecting six terminal olefins sequentially in one molecule under metathesis conditions, three macrocycles were formed efficiently in one pot yielding a novel cryptand with tetrahedral connectivity. |
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| Keywords: | Cryptand Host Macrocyclization Receptor Ring-closing metathesis |
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