Stereoselective synthesis of (+)-lauthisan |
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| Authors: | Hyun Joo Rhee |
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| Affiliation: | College of Pharmacy, Sookmyung Women’s University, Chungpa-dong, Yongsan-ku, Seoul 140-742, Republic of Korea |
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| Abstract: | Stereoselective synthesis of (+)-lauthisan has been accomplished starting from d-glyceraldehyde acetonide by combination of diastereoselective alkylation and ring-closing metathesis. High degree of 1,3-asymmetric induction has been realized in ether system. |
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| Keywords: | (+)-Lauthisan Diastereoselective alkylation Ring-closing metathesis Cyclic ether |
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