Rapid and efficient synthesis of optically active pyrazoles under solvent-free conditions |
| |
Authors: | J.S. Yadav B.V.S. Reddy P. Naga Lakshmi A.C. Kunwar |
| |
Affiliation: | a Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India b Centre for Nuclear Magnetic Resonance, Indian Institute of Chemical Technology, Hyderabad 500 007, India |
| |
Abstract: | 2-Formyl glycals undergo rapid condensation with arylhydrazines under solvent-free conditions to give the corresponding optically pure 4-substituted pyrazoles in good yields with high selectivity. The stereochemistry of the products was assigned by various NMR experiments. |
| |
Keywords: | Arylhydrazines 2-Formyl glycals Microwaves Pyrazoles |
本文献已被 ScienceDirect 等数据库收录! |