An unexpected simple synthesis of N-substituted 2-acetoxy-5-arylpyrroles and their hydrolysis to 3 and 4-pyrrolin-2-ones |
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| Authors: | Georgia Tsolomiti |
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| Institution: | The Laboratory of Organic Chemistry, The School of Chemical Engineering, The National Technical University of Athens, Athens 157 80, Greece |
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| Abstract: | The unexpected synthesis of N-substituted 2-acetoxy-5-arylpyrroles, from the reaction of 3-aroyl-propionamides with a large excess of refluxing acetyl chloride, and their alkaline hydrolysis to 3- and 4-pyrrolin-2-ones, is described. |
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| Keywords: | 2-Acetoxypyrroles 3-Pyrrolin-2-ones 3-Aroylpropionamides Acetyl chloride |
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