Novel parallel synthesis of N-(4-oxo-2-substituted-4H-quinazolin-3-yl)-substituted sulfonamides |
| |
| Authors: | Yuefen Zhou |
| |
| Affiliation: | Department of Medicinal Chemistry, Anadys Pharmaceuticals Inc., 3115 Merryfield Row, San Diego, CA 92121, USA |
| |
| Abstract: | A general method was developed to synthesize a class of N-(4-oxo-2-substituted-4H-quinazolin-3-yl)-substituted sulfonamides in moderate to good yield. This new method can be applied in both single compound and parallel synthesis. About 90 compounds with a variety of substituents were synthesized using this method in a parallel fashion. |
| |
| Keywords: | 3-Sulfonamide-substituted quinazolinones Parallel synthesis |
| 本文献已被 ScienceDirect 等数据库收录！ |
